Mpox (formerly known as monkeypox) is a viral illness that primarily spreads through skin-to-skin contact, although it can also spread through respiratory secretions during prolonged, face-to-face contact. It is endemic in some countries but not the United States, though several countries, including the United States, have seen cases in 2022.
Confirmed and probable cases in Maricopa County as of 11/29/2023
Data are updated monthly
|Confirmed and probable cases|
For more data, see the Centers for Disease Control (CDC) case counts map.
Other Locations Offering Vaccine
- Southwest Center
1101 N Central Ave #200, Phoenix, AZ 85004
Mpox vaccine is offered Monday-Friday from 8 a.m. - 3:30 p.m.
- Free Vaccines at Off Chute Too
4111 7th Avenue, Phoenix, AZ 85013
- Saturdays December 9, 16, and 23, 2023
12 - 4 p.m.
- Vaccines offered:
- Mpox (Jynneos) (ages 18+)
- COVID-19 (depending on availability)
- Hepatitis A & B (ages 19+)
- HPV (ages 19-26)
- Saturdays December 9, 16, and 23, 2023
Important Information About Second Doses
Second doses are recommended at least four weeks after the first dose. Maximum immunity from the vaccine is expected about two weeks after the second dose. The vaccine is the most effective weapon to stop the spread of the virus. Getting the second dose and completing the series is the best way to gain the highest level of protection for yourself, and those around you.
If you get infected before or after your first dose: CDC does not recommend vaccination after infection unless you are immunocompromised. Individuals who are immunocompromised are recommended to get two doses of the vaccine even if they have been infected.
Frequently Asked Questions
- Do I need a mpox vaccine if I’ve had the smallpox vaccine? What if I don’t know if I’ve had the smallpox vaccine?
Both JYNNEOS and ACAM2000 are smallpox vaccines that have been approved for use to prevent mpox. Because it is better tolerated with fewer side effects, Maricopa County Department of Public Health is only administering JYNNEOS vaccine to prevent mpox at this time.
If you have completed the prescribed course for either of these vaccines in the last 3 years, you do not need additional vaccination against mpox. Smallpox vaccination that occurred more than 3 years ago will likely provide some protection against mpox but is not considered fully protective. If your smallpox vaccine was greater than three years ago and you are eligible for Jynneos vaccine you should be vaccinated.
The side effects of Jynneos depend in part on whether it is injected subcutaneously or intradermally. In general, many people experience common, mild reactions, which usually go away without treatment within a day or two:
For the complete list and explanation of potential mpox/smallpox vaccine side effects, visit the CDC's page on vaccine side effects.
Clinical data indicates intradermal administration (injecting the vaccine between layers of the skin) of the JYNNEOS vaccine is effective in triggering a similar antibody response even at the lower dose.
For a detailed explanation of the JYNNEOS vaccine, visit the CDC's page on JYNNEOS vaccine.
The JYNNEOS vaccine is given in the tricep (subcutaneous) or the forearm (intradermal) because those locations allow for ease of positioning to the appropriate tissues. The vaccine injection route (subcutaneous or intradermal) puts the vaccine into the appropriate space to elicit the best immune response and ensure vaccine effectiveness.
JYNNEOSTM is administered as a live virus that is non-replicating. This means the virus has been genetically modified so that it cannot reproduce.
Mpox typically begins with:
- Muscle aches
- Swollen lymph nodes
- Respiratory symptoms (e.g. sore throat, nasal congestion, or cough)
Within 1 to 3 days (sometimes longer) after the appearance of fever, the patient develops a rash, often beginning on the face then spreading to other parts of the body.
- Some people experience a rash or sores first, followed by other symptoms and some people only experience a rash or sores
- The rash or sores are sometimes located on or near the genitals or anus, but sometimes in other areas like the hands, feet, chest or face – sores will go through several stages before healing (see below)
- Sores may be inside the body, including the mouth, vagina, or anus
The rash may begin as small, flat, round discolorations that become raised and fluid-filled (clear or pus) before scabbing. These spots and the fluid in them carry virus that can infect others. Once scabs fall off, the area is no longer infectious.
The illness typically lasts for 2−4 weeks. Most patients with Mpox fully recover from the virus without treatment.
If you have symptoms, including any unexplained rash: Please call your healthcare provider and inform them of your symptoms. If you do not have a healthcare provider, you can find one at 211 Arizona or call 602-506-6767 for assistance.
Mpox can spread to anyone through close, personal, often skin-to-skin contact including:
- Direct contact with mpox rash, sores, fluid, or scabs
- Contact with objects, fabrics (clothing, bedding, or towels), and surfaces that have been used by someone with mpox
- Through respiratory droplets or oral fluids from a person with mpox
This contact can happen during intimate sexual contact including:
- Oral, anal, and vaginal sex or touching the genitals or anus of a person with mpox
- Hugging, massage, or kissing and talking closely
- Touching fabrics and objects during sex that were used by a person with mpox
We know the virus can be spread in fluid or pus from mpox sores, and are trying to better understand if the virus could be present in semen, vaginal fluids or other body fluids.
According to the CDC, a person is more likely to develop mpox if they:
- Report having contact with a person or people with a similar appearing rash or who received a diagnosis of confirmed or probable mpox
- Had close or intimate in-person contact with individuals in a social network experiencing mpox activity; this includes men who have sex with men (MSM) who meet partners through an online website, digital application (“app”), or social event (e.g., a bar or party)
- Traveled outside the US to a country with confirmed cases of mpox or where Mpox virus is endemic
- Had contact with a dead or live wild animal or exotic pet that is an African endemic species or used a product derived from such animals (e.g., game meat, creams, lotions, powders, etc.)
Take the following steps to prevent getting mpox:
- Avoid close, skin-to-skin contact with people who have a new rash.
- Do not touch the rash or scabs of a person with mpox.
- Do not kiss, hug, cuddle or have sex with someone with mpox.
- Avoid contact with objects and materials that a person with mpox has used.
- Do not share eating utensils or cups with a person with mpox.
- Do not handle or touch the bedding, towels, or clothing of a person with mpox.
- Wash your hands often with soap and water or use an alcohol-based hand sanitizer, especially before eating or touching your face and after you use the bathroom.
Most people get well from mpox without needing any medicines or other treatment. There is no medicine that the FDA has approved for mpox treatment. However, Tecovirimat (TPOXX or ST-246) is an antiviral medication available for the treatment of mpox infection.
Maricopa County Department of Public Health cannot directly consult with the public on TPOXX. If you believe you could benefit from TPOXX, talk with your primary care provider and have your PCP reach out to MCDPH to discuss TPOXX treatment options.
As most cases of mpox resolve without treatment and are not severe, referral for testing to local emergency departments/urgent care centers is not usually necessary. Please see the SURV alert from 7/13/2022 for more details on testing options.
Please note: the phone number listed in the SURV alert is for provider use only. You may refer patients to the MCDPH CARES Team at (602) 506-6767.
For more healthcare provider information, visit our Healthcare Provider page.