Mpox (formerly known as monkeypox) is a viral illness that primarily spreads through skin-to-skin contact, although it can also spread through respiratory secretions during prolonged, face-to-face contact. It is endemic in some countries but not the United States, though several countries, including the United States, have seen cases in 2022.

Confirmed and probable cases in Maricopa County as of 11/29/2023

Data are updated monthly

Confirmed and probable cases

For more data, see the Centers for Disease Control (CDC) case counts map.

Mpox Vaccine

The vaccine for mpox, Jynneos, is available at MCDPH immunization clinics as well as some community events for individuals at risk for contracting mpox and for those who have been exposed to a person diagnosed with mpox. Call the CARES team at 602-506-6767 to discuss eligibility and to make an appointment for vaccination.

Other Locations Offering Vaccine

  • Southwest Center
    1101 N Central Ave #200, Phoenix, AZ 85004
    Mpox vaccine is offered Monday-Friday from 8 a.m. - 3:30 p.m.

Important Information About Second Doses

Second doses are recommended at least four weeks after the first dose. Maximum immunity from the vaccine is expected about two weeks after the second dose. The vaccine is the most effective weapon to stop the spread of the virus. Getting the second dose and completing the series is the best way to gain the highest level of protection for yourself, and those around you.

If you get infected before or after your first dose: CDC does not recommend vaccination after infection unless you are immunocompromised. Individuals who are immunocompromised are recommended to get two doses of the vaccine even if they have been infected.

More Information

Frequently Asked Questions

Both JYNNEOS and ACAM2000 are smallpox vaccines that have been approved for use to prevent mpox. Because it is better tolerated with fewer side effects, Maricopa County Department of Public Health is only administering JYNNEOS vaccine to prevent mpox at this time.

If you have completed the prescribed course for either of these vaccines in the last 3 years, you do not need additional vaccination against mpox. Smallpox vaccination that occurred more than 3 years ago will likely provide some protection against mpox but is not considered fully protective. If your smallpox vaccine was greater than three years ago and you are eligible for Jynneos vaccine you should be vaccinated.

  1. Signs & Symptoms
  2. Transmission
  3. Prevention
  4. Treatment
  5. Healthcare Providers

Mpox typically begins with:

  • Fever
  • Headache
  • Muscle aches
  • Backache
  • Swollen lymph nodes
  • Chills
  • Exhaustion
  • Respiratory symptoms (e.g. sore throat, nasal congestion, or cough)

Within 1 to 3 days (sometimes longer) after the appearance of fever, the patient develops a rash, often beginning on the face then spreading to other parts of the body.

  • Some people experience a rash or sores first, followed by other symptoms and some people only experience a rash or sores
  • The rash or sores are sometimes located on or near the genitals or anus, but sometimes in other areas like the hands, feet, chest or face – sores will go through several stages before healing (see below)
  • Sores may be inside the body, including the mouth, vagina, or anus

The rash may begin as small, flat, round discolorations that become raised and fluid-filled (clear or pus) before scabbing. These spots and the fluid in them carry virus that can infect others. Once scabs fall off, the area is no longer infectious.

The illness typically lasts for 2−4 weeks. Most patients with Mpox fully recover from the virus without treatment.

If you have symptoms, including any unexplained rash: Please call your healthcare provider and inform them of your symptoms. If you do not have a healthcare provider, you can find one at 211 Arizona or call 602-506-6767 for assistance.

More on signs and symptoms from CDC